TQ Quiz | Trending Topics in Neuro-Ophthalmic Disease (Nashville 2024)

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1. Which of the following first generation MS drugs has the longest duration of action?*

A - Plegridy

B - Copaxone

C - Betaseron

D - Avonex

2. All of the following oral medications has a risk factor of cystoid macular edema EXCEPT:*

A - Gilenya (fingolamod)

B - Tecfidera (dimethyl fumarate)

C - Mayzent (siponimod)

D - Ponvory (ponesimod)

3. Which of the following MS drugs has the highest risk of PML?*

A - Aubagio (teriflunamide)

B - Gilenya (fingolamod)

C - Tecfidera (dimethyl fumarate)

D - Tysabri (natalizumab)

4. Which of the following inflammatory diseases is most likely to cause bilateral/simultaneous optic neuritis?*

A - Myelin oligodendrocyte glycoprotein disease

B - Multiple sclerosis

C - Neuromyelitis optica

D - Sarcoidosis

5. Which of the following is FDA approved for the systemic treatment of giant cell arteritis?*

A - Actemra (tocilizumab)

B - Rituxan (rituximab)

C - Prednisone

D - Tepezza (teprotumumab)

6. Which obesity related PTC patient with papilledema can be managed without medication?*

A - Opening pressure of 450 mm H2O with no headaches and no impact on optic nerve structure or function

B - Opening pressure of 280mmH2O with constant headaches and no impact on optic nerve structure or function

C - Opening pressure of 300mmH20 with no headaches, arcuate VF loss and thinning of the GCC bilaterally

D - Opening pressure of 310 mmH20 with no headaches and no impact on optic nerve structure or function

7. All of the following are true regarding Topiramate in the treatment of PTC EXCEPT:*

A - It has been associated with angle closure secondary to choroidal effusion

B - Its inhibition of carbonic anhydrase is superior to that of Diamox

C - It has an important use in treating headaches associated with increased ICP

D - It promotes weight loss

8. What amount of weight loss is generally considered to be effective in bringing about remission in obesity related PTC?*

A - 3%

B - 10%

C - 15%

D - 25%

9. An obese patient with chronic intracranial hypertension has been under your care for over a year. She is asymptomatic and is also non-compliant with Diamox due to side effects. Topamax was similarly problematic. She has persistent papilledema and is now demonstrating thinning of her GCC with arcuate visual field loss. What is the best management option?*

A - Weight loss

B - Bariatric surgery

C - Optic nerve sheath fenestration

D - Add prednisone to her medication regimen

10. A 250lb female with chronic intracranial hypertension has significant thickening of her RNFL on OCT. Her GCC/IPL is intact and her visual fields are normal. She has no visual symptoms and is not experiencing headaches. What is the most appropriate management plan?*

A - Attempt weight reduction with a target weight of 225 lbs

B - Diamox

C - Topamax

D - Bariatric surgery

11. A 250lb female with chronic intracranial hypertension has significant thickening of her RNFL on OCT . Her GCC/IPL is intact and her visual fields are normal. She has no visual symptoms, but is experiencing severe headaches. What is the most appropriate management?*

A - 25 lb weight reduction without medication

B - Diamox

C - Topamax

D - Bariatric surgery

12. A 250 lb female presents with severe headaches and bilateral disc edema that is consistent with papilledema. Her optic nerves demonstrate grade 5 papilledema and there are numerous hemorrhages and exudates. Blood pressure is 140/90. What is the most appropriate management plan?*

A - Referral to the ER for emergent diagnostic work up

B - Begin a high dosage of Diamox

C - Begin treatment with Topamax

D - Order an MRI and MRV, followed by a lumbar puncture

13. What is considered to be the gold standard in the diagnosis of myasthenia gravis?*

A - Tensilon Test

B - Antibody testing

C - Thoracic CT

D - EMG

14. All of the following are implicated in the pathophysiology of obesity related PTC EXCEPT:*

A - Mechanical factors

B - Cellular factors

C - Endocrine factors

D - Iron deficiency

15. Diagnostic testing for giant cell arteritis includes all of the following EXCEPT:*

A - ESR/CRP

B - TA Biopsy

C - MR venogram

D - Arterial ultrasound

16. All of the following are true regarding giant cell arteritis EXCEPT:*

A - Fast track programs in emergency settings are useful in expediting diagnosis and treatment

B - The carotid vasculature is the most frequent target of the vasculitic process

C - Tocilizumab has been shown to reduce the dosage of prednisone and bring about more sustained remission

D - Arteritic ischemic optic neuropathy shows rapid improvement with corticosteroids

17. All of the following are useful in the treatment of ocular myasthenia gravis EXCEPT:*

A - Eculizumab (Solaris)

B - Corticosteroids

C - Mestinon

D - Azothioprine

18. MRI findings suggestive of NMO occur in which part of the brain?*

A - Periventricular

B - Diencephalon/medulla

C - Cerebellar

D - Cerebral cortex

19. Which of the following is true regarding myasthenia gravis?*

A - It affects involuntary muscle

B - It has a predilection for muscles innervated by cranial nerves

C - It has a variable presentation

D - It is characterized by fatiguability

20. Which MS medication poses a risk to both male and female offspring?*

A - Aubagio (teriflunamide)

B - Gilenya (fingolimod)

C - Vumerity (diroximel fumarate)

D - Tecfidera (dimethyl fumarate)

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