TQ Course | Ocular Biologics, Biosimilars, and Drugs for the Eye Questions for What’s the Difference and What’s New (Mackinac Island 2021)

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Ocular Biologics, Biosimilars, and Drugs for the Eye What’s New
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1. Which class of drugs are produced using a living system, such as a microorganism, plant cell, or animal cell?*
- A - Opioid drugs
- B - Analgesic drugs
- C - Antiviral drugs
- D - Biologic drugs
2. Currently available biologic drugs DO NOT include which of the following?*
- A - Bacteria
- B - Yeast
- C - Human cells
- D - Viruses, like COVID 19
3. The manufacturing process of a biologic drug is closest to ______________?*
- A - organic chemistry
- B - genetic engineering
- C - inorganic chemistry
- D - analytical chemistry
4. When comparing the size of a chemically synthesized drug to a biologic drug, generally biologics are ___________________________?*
- A - much smaller the new nanotechnology
- B - generally slightly smaller
- C - the same size as chemically synthesized drugs
- D - larger in size
5. When comparing the complexity of a chemically synthesized drug to a biologic drug, which of the following is true?*
- A - Biologics are more complex.
- B - Biologics and chemically synthesized drugs are equally complex.
- C - Biologics are slightly less complex.
- D - Biologics are simple molecules.
6. Most biologic drugs are given________?*
- A - orally
- B - sublingually
- C - as an injection or infusion
- D - rectally
7. Which term most closely fits the following definition: “A biologic medical product, also known as a biologic that is highly similar to another already approved biologic medicine or the reference medicine”?*
- A - Generic medication
- B - All-purpose biologic
- C - Copycat biologic
- D - Biosimilar drug
8. Which biologic drug is indicated for eye care and is the only one administrated as an eye drop?*
- A - Teprotumumab-trbw (Tepezza)
- B - Cenegermin –bkbj (Oxervate)
- C - Tocilizumab (Actemra)
- D - Adalimumab (Humira)
9. Which biologic drug is indicated for thyroid eye disease?*
- A - Teprotumumab-trbw (Tepezza)
- B - Cenegermin–bkbj (Oxervate)
- C - Tocilizumab (Actemra)
- D - Adalimumab (Humira)
10. Which biologic drug is indicated for the treatment of neurotrophic keratitis?*
- A - Teprotumumab-trbw (Tepezza)
- B - Cenegermin–bkbj (Oxervate)
- C - Tocilizumab (Actemra)
- D - Adalimumab (Humira)
11. Which biologic drug is indicated for the treatment of giant cell arteritis (GCA) in adult patients?*
- A - Teprotumumab-trbw (Tepezza)
- B - Cenegermin–bkbj (Oxervate)
- C - Tocilizumab (Actemra)
- D - Adalimumab (Humira)
12. Which biologic drug is indicated for the treatment of non-infectious intermediate, posterior, and panuveitis in adults and children 2 years of age and older?*
- A - Teprotumumab-trbw (Tepezza)
- B - Cenegermin–bkbj (Oxervate)
- C - Tocilizumab (Actemra)
- D - Adalimumab (Humira)
13. Which of the following ocular biologic drugs is NOT indicated for the treatment of neovascular (wet) age-related macular degeneration?*
- A - Bevacizumab (Avastin)
- B - Teprotumumab-trbw (Tepezza)
- C - Brolucizumab-dbll (Beovu)
- D - Ranibizumab (Lucentis)
14. All of these ocular biologic drugs are indicated for the treatment of neovascular (wet) age-related macular degeneration. Which recently approved biologic was effective in over 50% of the patients at a dosing frequency of 12 weeks between treatments?*
- A - Bevacizumab (Avastin)
- B - Aflibercept (Eylea)
- C - Brolucizumab-dbll (Beovu)
- D - Ranibizumab (Lucentis)
15. Which of the following mechanisms most closely describes how Teprotumumab-trbw (Tepezza) works?*
- A - It binds to IGF-1 receptor and blocks its activation and signaling.
- B - It is an exact copy human nerve growth factor.
- C - It blocks vascular endothelial growth factor.
- D - It binds to TNF and blocks its action in the body.
16. Which of the following mechanisms most closely describes how Adalimumab (Humira) works?*
- A - It binds to IGF-1 receptor and blocks its activation and signaling.
- B - It is an exact copy human nerve growth factor.
- C - It blocks vascular endothelial growth factor.
- D - It binds to TNF and blocks its action in the body.
17. Which of the following mechanisms most closely describes how cenegermin–bkbj (Oxervate) works?*
- A - It binds to IGF-1 receptor and blocks its activation and signaling.
- B - It is a recombinant form of human nerve growth factor.
- C - It blocks vascular endothelial growth factor.
- D - It binds to TNF and blocks its action in the body.
18. Which of the following mechanisms most closely describes how Brolucizumab-dbll (Beovu) works?*
- A - It binds to IGF-1 receptor and blocks its activation and signaling.
- B - It is a recombinant form of human nerve growth factor.
- C - It blocks vascular endothelial growth factor.
- D - It binds to TNF and blocks its action in the body.
19. Baricitinib (Olumiant) and upadacitinib (Rinvoq) are biologic drugs approved to treat moderate to severe rheumatoid arthritis. They are unique because they are taken _________.*
- a. orally
- b. sublingually
- c. as an injection or infusion
- d. rectally
20. Erenumab-aooe (Aimovig) and fremanezumab-vfrm (Ajovy) are monoclonal antibody biologic drugs that target the calcitonin gene-related peptide receptor for the prevention of ___________?*
- A - rheumatoid arthritis
- B - thyroid eye disease
- C - migraines in adults
- D - giant cell arteritis in adults
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TQ Course | Ocular Biologics, Biosimilars, and Drugs for the Eye Questions for What’s the Difference and What’s New (Mackinac Island 2021)

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