TQ Quiz | Eye Can't Get No Satisfaction: New Solutions for OSD (Scottsdale 2026)

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1. Which TFOS DEWS III update best defines Dry Eye Disease?*

A - Evaporative loss due to meibomian gland dropout

B - A disease of tear film homeostasis with ocular symptoms

C - A multifactorial disease of the ocular surface characterized by loss of homeostasis of the tear film

D - A purely aqueous deficiency–driven condition

2. Which drug candidate is a TRPM8 receptor agonist designed to increase basal tearing?*

A - Reproxalap

B - Acoltremon

C - Perfluorohexyloctane

D - AZR-MD-001

3. What is the mechanism of action for Acoltremon (AR-15512)?*

A - Immunomodulation via calcineurin inhibition

B - Cyclooxygenase-2 inhibition

C - Activation of corneal cold receptors to stimulate tear secretion

D - Meibomian gland anti-inflammatory effect

4. Which of the following best explains why autologous serum tears are effective for dry eye disease?*

A - They provide antibiotic properties that sterilize the ocular surface

B - They mimic natural tears by supplying growth factors, proteins, and immunoglobulins

C - They increase intraocular pressure and stimulate aqueous production

D - They neutralize tear film osmolarity by reducing sodium chloride

5. Which component of blood is concentrated in PRP and considered a “powerhouse for healing”?*

A - Red blood cells

B - White blood cells

C - Platelets

D - Plasma proteins

6. Perfluorohexyloctane is notable for lacking which component?*

A - Fatty acid

B - Emulsifier

C - Preservatives

D - Osmoprotectants

7. Which investigational ointment targets abnormal keratinization in meibomian gland dysfunction?*

A - Reproxalap

B - Acoltremon

C - AZR-MD-001

D - Thealoz Duo

8. What is the concentration of topical vitamin D drops being studied for MGD?*

A - 100 IU/mL

B - 500 IU/mL

C - 1000 IU/mL (25 µg/mL)

D - 5000 IU/mL

9. Which topical therapy is currently in Phase 4 trials for MGD-related symptoms?occlusion?*

A - AZR-MD-001

B - Vitamin D drops

C - Topical hydrocortisone

D - Reproxalap

10. Which of the following is not a common reason to use compounded ophthalmic therapy?*

A - High patient out-of-pocket costs

B - Need for preservative-free formulations

C - Access to discontinued drugs

D - To bypass standard safety testing

11. Which compounded drug has shown benefit in improving corneal scarring?*

A - Tacrolimus

B - Cyclosporine

C - Losartan

D - PHMB

12. Which compounded medication is used in neurotrophic keratitis management?*

A - Tacrolimus

B - Cyclosporine

C - Insulin

D - Losartan

13. Ranibizumab 100 mg/mL implant gained additional FDA indications in 2025 for:*

A - Retinitis pigmentosa

B - Central serous chorioretinopathy

C - Diabetic macular edema and diabetic retinopathy

D - Retinal vein occlusion

14. What technology underlies the Valeda system’s therapeutic effect?*

A - Ultrasound-mediated photocoagulation

B - Excimer laser photoactivation

C - Multi-wavelength photobiomodulation (LLLT)

D - Thermal ablation

15. The Valeda® Light Delivery System treats which condition?*

A - Neovascular AMD

B - Intermediate dry AMD

C - Diabetic macular edema

D - Retinitis pigmentosa

16. The goal of photobiomodulation (LLLT) therapy for AMD is to:*

A - Replace retinal tissue

B - Reduce intraocular pressure

C - Improve mitochondrial function and retinal metabolism

D - Dilate retinal vessels

17. Perfluorohexyloctane is a new treatment for:*

A - Allergic conjunctivitis

B - Meibomian gland dysfunction-related dry eye

C - Glaucoma

D - Uveitis

18. Topical vitamin D drops are being studied for improvement in:*

A - Retinal function

B - Optic nerve perfusion

C - Meibomian gland function

D - Accommodation amplitude

19. Compounded medications can be beneficial because they:*

A - Are always cheaper than branded drugs

B - Can be customized for concentration and preservative-free needs

C - Do not require prescriptions

D - Are FDA-approved in every case

20. The Leos™ Laser Endoscopy Ophthalmic System combines endoscopy with what for glaucoma surgery?*

A - Trabeculectomy flap

B - Laser cyclophotocoagulation

C - Micro-stent placement

D - Canaloplasty

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